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Fusarium wilt disease is one of the major plant diseases that affect tomato productionneem oil wilko  The soap will kill insects on contact through mechanical action and suffocation, while the oil will also repel them and interfere with their feeding, mating, and egg-laying

10 drops lavender essential oil (optional) Place neem and coconut oil in a bowl and mix well and use. 8% neem oil solution (about 30 ml of neem oil per 3785 ml of water), which is used in gardening as a natural pest repellent and insecticide. 1. com Neem comes from the Indian lilac tree. Leafy greens: the leaves of leafy greens such as spinach and lettuce are fragile, and neem oil can quickly cause leaf burns. Neem Oil 16 Oz/473ml-100% Natural and Pure, and Cold-Pressed by Oreola Naturals. 33. Add outdoor lighting to create the perfect ambience so. Crushed crab shells can be worked into the soil or used as a mulch to provide your plants with a long-lasting source of nitrogen. , it doesn’t cause ulcers). This insect and leaf miner spray effectively gets rid of all the bugs that want to feast on your plants, like your dwarf lemon tree. Main benefits: Soothes scalp inflammation, treats dandruff, smoothes frizz. Start spraying from the bottom of the plant and make your way up. This is not a combination product either, so it will require a top coat like spar urethane over the. Add 1-2 teaspoons of a liquid soap, like this one. Fill it with water, then add a few drops of liquid soap. Neem oil can be used to keep pests away and to get rid of pests that are already there in an existing infestation. Neem oil is also a great conditioner that has fatty acids that soften and smooth your hair. Among them, the major constituents are triterpenes known as limonoids, the most important being azadirachtin (Figure 1 ), which appears to cause. In recent years, it has become increasingly popular for its potential to treat a number of penis-related ailments, including dryness. 78 Ounces. Ulcers A small study found neem bark extract effective in reducing stomach acid secretion without any adverse effects. Neem oil is most effective on plants with smooth surfaces because it prevents pests from crawling deeper into the leaves and escaping the oil’s effects. And a little bit goes a long way. Neem has notable antifungal properties that seem to work well on roses. If you cannot take your plant (s) outdoors to thoroughly spray them, clean the plant and wipe it down with a mixed neem oil solution. Dilute the oil by combining two teaspoons of Neem oil for each gallon of water. Get directions. It is yellow to brown, has a bitter taste, and a garlic/sulfur smell. After the water and soap are mixed, add a small amount of neem oil, one to two tablespoons per gallon of water, or one to two teaspoons per quart of water. Neem oil contains Azadirachtin, which is the active agent that repels and kills bugs. It’s safer to use than a synthetic pesticide but it is still not totally safe. tb1234. Standard liquid dishwashing soap, preferably non-phosphate, does a perfect job. In this case the ratio is 4ml of oil per liter of water and it should be sprayed every 10 days. Find amazing deals on neem oil wilko at on Temu. Put all of the ingredients into a spray bottle, and shake it up well. 1. for use on roses, flowers, fruits and vegetables. We would like to show you a description here but the site won’t allow us. That means you’d have to spray it on each and every bed bug in your home to fully eradicate the problem. The neem oil was produced locally in Kilifi County, coastal Kenya and sent to an ISO 9001:2015 certified laboratory prior to use for testing for potential contaminants according to WHO guidelines. [6] Eliminates Scars. NEEM OIL BENEFITS. The solid residue left after the oil is removed from the kernels is employed as a fertilizer and soil. Pyrroles: These chemicals affect cell. Neem oil is higher in palmitic acid than argan oil, another fantastic hair and skin moisturiser. Mix the solution vigorously. This is because neem oil can cause these plants to produce fewer flowers and fruits. 48 Translation. DIY Moth Repellant Spray. When To. Cold-pressed if you want to be fancy. If you’re able to, turn the plants 360 degrees to make sure all parts are evenly covered. Simply loosen the topsoil to a depth of 1 inch around the plant, then apply 5-10gm of neem powder evenly over the top. The answer is yes. Neem Oil Spray for Plants. This makes it harder for insect pests to grow and lay eggs. lice combs can also be used to remove lice from chickens. Non greasy. Don’t inhale the mist. Breathe easy. Studies have shown that neem oil can effectively kill the spores of black mold, thereby reducing the risk of respiratory problems and other health issues. Aim: The aim of this study was to evaluate the effect of oil pulling with neem oil on plaque induced gingivitis and compare its efficacy with oil pulling with coconut oil. Healthy hair. 32. For Organic gardening. Step 3: Commercial Black Spot Sprays Neem oil: Neem is an organic fungicide and pesticide, derived from the seeds of the neem tree. Neem oil has a strong, pungent odor, and is commonly used in traditional medicine for. Sometimes pure, other times diluted. Neem (Azadirachta indica) is recognized as a medicinal plant well known for its antibacterial, antimalarial, antiviral, and antifungal properties. Avoid contact with your eyes, and do not directly. But some ants can be problematic to a plant, feeding on its leaves themselves. And many plants can be damaged due to neem oil. It helps manage populations of a variety of pests, including: Aphids Thrips Whiteflies Mealybugs Spider mites Caterpillars Nematodes Scale WhitefliesNeem oil, also known as margosa oil, is a vegetable oil pressed from the fruits and seeds of the neem ( Azadirachta indica ), a tree which is indigenous to the Indian subcontinent. tb1234. BEST FOR MATTRESSES: PT Alpine Flea & Bed Bug Pressurized Insecticide. Look out for a white, sticky substance that looks a bit like cornmeal, which is a key sign of mealybug presence. Crab meal. The discount chain B&M has struck a deal to buy 51 Wilko stores for up to £13m as the stricken retailer’s administrators rush to seal last-minute deals with the fate of thousands of jobs. Using Neem Oil on Garden Plants. e. Know The Flip Side: Neem. It slowly kills insects and gradually prevents them from re-establishing. Bronchitis is another. In vivo studies in rats (20), rabbits (8), rhesus monkeys (14), and human volunteers (10) proved that neem oil applied intravaginally before sexual intercourse prevented. Repeat the process every two weeks to keep African violets pest-free. Next, mix one gallon of warm water with one teaspoon of liquid soap. It can kill insect eggs. We DO NOT recommend spraying any type of insecticide indoors. Neem oil (made from neem seeds) contains low concentrations of aflatoxin that are poisonous in large doses. Additionally, it is important to note that neem oil can damage some fabrics and materials, so it is important to be mindful of where and when it is used. The study showed that neem oil was significant on Liriomyza spp by revealing an average number of 4. Completely safe, biodegradable and 100% free of chemicals. 2 tbsp Neem is sufficient for powerful effects, so make sure to use it liberally. 7) Bacterial and Fungal Infections. Detoxify blood. Safe Doses of Neem Oil for Dogs. Keywords – Neem oil, Extraction, Natural, Treatment. Leave the neem oil on the plant for 24 hours before rinsing it off with warm water and wiping down the leaves gently with a soft cloth. Returns accepted. Without affecting libido, neem oil can lower the fertility level, prevent sexually transmitted diseases. It is available as an oil or extract. It is deep yellow in color and has garlic–like odor. The residue is Neem cake which is used in agriculture as a soil amendment, protecting the roots and enhancing plant growth. Clarified hydrophobic neem oil is the active ingredient in ready-to-use neem oil sprays that can be picked up at a garden center. As an insecticide, neem oil is pretty effective. Neem oil is rich in fatty acids. 6. 1 tsp unfiltered neem oil. Lace bugs. Neem oil is effective in all stages of insect growth. Neem Oil unrefined cold pressed helps to restore moisture & promote soft, supple skin. The top adverse reaction is listed as increased muscle activity in 56 cases. Neem oil comes in a variety of different colors, including red, yellow, and brown. 5 Neem oil is being employed as well. When administered topically, dilute pure neem oil with a. At this time, there is limited information regarding known interactions with different medications because of limited human research. A mixture of 2 percent neem oil and coconut oil provided 96 to 100 percent protection from one type of mosquito, 85 percent from. Neem can reduce the chance of conception without causing any harm to the system. Improve liver function. Fill a garden sprayer with enough water to get the job done. In this study, the in vitro antifungal activity of neem oil (0. Neem oil is a botanical insecticide made of natural tree oil, harvested from its seeds, and has a low toxicity rating. It’s a great oil, but. Neem oil is derived from the seeds and fruits of the neem plant. Last modified on Mon 28 Nov 2022 11. Apply the solution to the base of the tomato plants. Directly tied to many of its benefits – including those for skin, hair, and oral health – neem oil is a potent antiseptic. Pet parents ask, is neem oil toxic to dogs, and the answer is no. Grow rose varieties that are resistant to black spot. Rupani says. A pound of neem cake will cover a 20- by 20-foot area and stand at a depth of 6 inches. Add ¾ ounce of mild soap to the neem juice and mix well. Extracted from the seed of a neem tree growing in South Asia. Directions: For inhalation or external use on unbroken skin only. Neem oil is extracted from oil seed kernels, with active ingredients like azadirachtin, nimbin, picrin, and sialin. Add the neem oil and powdered tulsi leaves to honey and mix well. Treehugger / Lexie Doehner. Since antiquity neem has been renowned for healing. 318. 28 per ounce. The effect of neem oil, blended with various loading of GNPs on the friction and wear characteristics has been investigated. Wipe on a couple coats of BLO on furniture, trim, or any bare wood and let it dry until it. ALM 2 Stroke 1L Engine Oil. It is an oil-based, semi-transparent stain, so it does add some color but it also lets the grain of the wood show through still. However, not always by direct contact, depending on the bug. Natria Neem Oil is an easy to use option for Listed pests and diseases. 2. Pour the solution into the ground around your plant and allow it to absorb completely. and some vegetable oil (any kind of it) You kist need to mix one tablespoon of the liquid dish soap and one tablespoon of vegetable oil with a quart of water. Mix the water, neem oil, and soap in a large container. Neem oil can even rid common pests and fungus-causing fungi. According to the manufacturer’s specifications, the Viagrow 32 oz. Cold-pressed if you want to be fancy. What's more, neem oil increased type I collagen and elastin in the skin—two essential factors that contribute to skin aging at its core. At this time, there is limited information regarding known interactions with different medications because of limited human research. Simply add a few drops to a cotton ball and toss it into the bottom of the can to eliminate unpleasant smells and freshen up your home with a pleasing, earthy scent. Add 10ml (2 teaspoons) of the white oil concentrate into a spray bottle. Dilutions at 25% and 50% were also positive at 48 and 96 hours ( Fig. reduce. Rolling coverage of the latest economic and financial news, as Brent crude hits its highest level of 2023. Adding neem oil to a worm bin is a great way to keep pests and pathogens away, while also providing essential nutrients to the soil. February 27, 2023 Neem oil. for pricing and availability. Crab meal contains chitin and chitosan, two natural compounds found in crab shells that give them structure. It does work! Give it time to work. Read the Patient Information Leaflet before use. When used on a regular basis, neem oil regulates the oil secretion in the scalp for a healthier scalp and strong hair. Add 1-quart water and 1 tsp. It can kill insect eggs. Mix the Neem oil and Castile soap in a container and pour the solution into a spray bottle of water. Sometimes pure, other times diluted. It promotes hair growth, reduces dandruff and dryness, and prevents hair loss. It’s a long list including convulsions, tremor, twitching, ataxia, lethargy and hyper- salivation. /gal. It can cause leaf curl when used in hot weather. Oil. Captain Jack’s Neem Max Concentrate is approved for organic gardening. This can be an effective immediate remedy, but it may need to be repeated since it doesn’t prevent blackfly from returning. £2. Neem oil is higher in palmitic acid than argan oil, another fantastic hair and skin moisturiser. In general, neem oil is known to have fungicidal qualities that’ll help with various destructive fungi. 你可以在園藝店買配好的 Neem Oil,也可以到印度人開的店買純的楝樹油,再自己兌水。使用時,如果是純楝樹油,可以用一茶匙的純楝樹油,配以一公升清水,再加半茶匙的肥皂水。加肥皂水是讓其有附著力。沒有肥皂水,可以用洗碗的dishwasher liquid,有同樣作用。 Adverse effects on cats by neem oil as listed by a study. for use on roses, flowers, fruits and vegetables. Some people use neem oil to treat various skin conditions, including infections and acne. Make a paste of a few neem leaves and a few drops of shampoo by grinding them into a thick paste. That isn’t reason to panic, because most insects on plants are relatively harmless, and if you keep your plants happy with suitable. Neem Oil Insecticide. 5 tulsi leaves (dried and powdered) 3 tablespoons neem oil. Add the neem oil in a spray container, prior to application. Neem Oil Is Anti-Inflammatory. It is made using only potassium which produces a milder, softer soap than sodium. You will have to make a larger neem oil solution to use as a foliar spray. 1. Neem oil is a natural pesticide, fungicide and insecticide that has been used widely in traditional medicinal practices. Product Information. Form: Liquid. Neem oil is an excellent insect repellent that works against a wide range of bugs, including aphids, whiteflies, and spider mites, and is an eco-friendly product that will not harm your. Find the Indian distributor Parkers, They'll ship you a free sample. Neem oil sprays have some fungicidal activity, but it is typically limited to powdery mildew control. This will create a protective barrier on your skin locking in moisture and making the skin soft. Neem oil is completely safe for humans, animals, and plants. Potential hair and scalp benefits of amla oil include: strengthen the scalp and hair. Both oils are effective solutions for pest control and can be used to protect plants and trees. A good, pre-mixed product will set you back between $. The earliest Sanskrit medical writings refer to the benefits of its fruits, seeds, oil, leaves, roots, and bark. Neem oil boasts an impressive list of health benefits, including its ability to provide hair care and skincare, protect the immune system, detoxify the body, boost oral health, repel insects, increase appetite, soothe inflammation, and benefit heart health among others. Doesn't post to United States. to. It has a half-life of 3 to 22 days in soil and only 45 minutes to 4 days in water. products. Neem oil has a variety of uses. Squeeze the crushed leaves to extract as much juice as possible. Gaumond's recipe. Use Harris Neem Oil on a variety of flowering and potted. Neem Oil kills and repels ants at the same time. 8% neem oil solution (about 30 ml of neem oil per 3785 ml of water), which is used in gardening as a natural pest repellent and insecticide. Save 5% on any 4 qualifying items. The tree grows profusely in India, where people have great respect for neem’s healing powers. Neem Oil prevents STD. Neem oil for dogs can help reduce itchiness with allergies, treat skin infections, fight fungal infections, and has even been shown to treat mange and ringworm ( 3, 5 ). In other words, if you’re applying neem oil every 1, 2, or 3 days, you’re using it too much, and you could do slow but lasting damage to your plants. (12) Email when in stock. Clarified hydrophobic neem oil, is an oil, and as such it does coat insects and can suffocate certain types of insects, including adults. The bark, leaves, and seeds are used to make medicine. This soap is specially made to be mild on plants. The fatty acid present in this oil helps to remove impurities and tighten pores. Apply neem oil and don’t let acne. Neem oil is a type of vegetable oil extracted from the fruits and seeds of the neem tree (Azadirachta indica), a fast-growing evergreen tree that is native to the Indian subcontinent. The Big Cheese Ultra Power Mouse Traps. Effects on Other Organisms. Neem oil offers a natural solution to dog health issues and poses no threat of harm. 8 tablespoons coconut or olive oil. Closed Today. All you need is: water. 30 days. This study aimed to formulate an herbal shampoo and understand the. This one's trending. The high fatty acid and vitamin E content in neem oil also helps remove scars associated with acne. Fill the spray bottle with 1 litre of water, and put the lid on. <See a compilation of researches here> (until 2005). 98/l) Was: £12. Use a Q-Tip dipped in your Neem Oil water mix to remove pests. Garg / Wikimedia Commons / CC BY 3. Where indicated, the fluorescent probe pyrene (4 mM) was added to the surfactant/oil mixture before NE preparation. Since antiquity neem has been renowned for healing. 49 EST. FREE delivery Wed, Nov 22 on your first order. 99. Neem oil is largely considered safe to use in the garden. It is yellow or green in color and has a strong odor. Neem oil contains a number of active constituents that can be effective in the management of Acne vulgaris via different mechanisms. It contains active ingredients like azadirachtin, nimbin, picrin, and sialin. Assuming it comes into contact with the fungus at the earliest possible stage, neem oil can theoretically kill off the spores that have invaded it. Step 1: Mix neem oil, which is an organic insecticide. Image Credit: Stella de Smit via Unsplash As an insecticide, neem oil can be a great way to keep your plants healthy and free of pests. Neem oil is a vegetable oil that is extracted from the seeds of the neem tree, a plant that is native to India and other parts of the Indian subcontinent. soothe frizz. Remember to start treatment at the earliest sign of infection. There are several ways you can apply Neem Oil to your plants: Add Neem Oil to a spray bottle and mist your plants. If the spray hasn’t caused any discoloration or singing, you know you’re good to go. This product arrives conveniently ready-to-use with an attached trigger sprayer. M. Neem leaf is used for leprosy, eye disorders, bloody nose, intestinal worms, stomach upset, loss of appetite, skin ulcers, diseases of the heart and blood vessels (cardiovascular disease), fever, diabetes, gum disease (), and liver. Thoroughly spray the plant's leaves, ensuring comprehensive coverage, including the undersides. 51. Studies suggest that neem has blood sugar lowering effects. Shake the sprayer regularly to keep the solution mixed. Simply spray neem. There are three possible outcomes after an insect ingests neem oil: • It can prevent insects from reaching their next growth stage. Ultraviolet spectroscopy analysis indicated that 10% of neem oil was loaded with capsule. When used properly, there are many beneficial properties of neem oil with dogs to help them feel their best. In fact, the oil can cause damage to some plants that may not respond well to it. You’ll also need to get your hands on some cold-pressed neem oil, water, and dish soap. Put on gardening gloves. £7. temporarily seal hair follicles. 0. 1 C). To make your own neem oil insect repellent spray, you’ll need a spray bottle, liquid soap, cold-pressed neem oil, and a gallon of water. /gal. Sort & Filter. Almond oil is rich in fatty acids, proteins, and carbohydrates. Mix your neem oil concentrate, liquid soap, and water in a garden sprayer. Therefore, neem oil uses for plants as a pesticide have been acknowledged over the past few years. Spray the solution on areas where mosquitoes breed or rest, such as ponds, puddles, gutters, trash cans, flower pots, etc. Being home is a supposed to be about relaxing, and the last thing you want is for that to be interrupted by pests! Our range of pest controls, insect killers. It works against things like scale, mealybugs, leafhoppers, mites, whiteflies and aphids, but it does not control many of the other insects that are controlled by neem oil. Viewing 12 of 12 products. css"> <iframe src="height="0". Win-win situation. Re-Apply Regularly. Therefore, taking neem with diabetes medications, such as metformin, could cause blood sugar to drop too low. Neem oil is a natural bed bug repellent that is safe to use around children and pets. Protect your garden from pests with Wilko‰Ûªs bug killer range. GREAT FOR DRY SKIN - Neem seed oil is great for dry skin and locking in moisture. Strain the liquid through muslin cloth again to remove leftover leaves and debris. Neem Oil. Azadirachtin-rich extract (neem-aza) was 10 times more potent than crude neem oil (neem oil) against P. Directions: For inhalation or external use on unbroken skin only. You can also use household neem oil for making a rose fungicide. Captain Jack's neem oil kills eggs, larvae and adult stages of insects to provide full range protection against pests;and insects; this product kills spider mites,. tb1234. The neem tree is commonly used as a traditional panacea for skin ailments in India. Neem oil (azadirachtin) is long known as a natural insecticide or medication for humans and animals. It's also. 2. While horticultural oils prevent plant pests and disease invasion, neem oils repel and inhibit pests’ growth. It will reduce insect feeding and makes it harder for insects to reproduce. Spray infested areas with this natural repellent. Neem oil, a plant-derived product rich in bioactives, has been incorporated in liposomes and hyalurosomes modified by adding argan oil and so called argan-liposomes and argan-hyalurosomes. Pursonic. Because neem has anti-inflammatory properties, it can be used to relieve pain caused by arthritis. It can burn their leaves, so I recommend insecticidal soap in this case. Among them, the major constituents are triterpenes known as limonoids, the most important being azadirachtin ( Figure 1 ), which appears to cause 90% of the effect on most pests. This one's trending. Neem oil is useful in healing inflammation, which is often marked by redness, swelling, and pain. Mix ¼ cup of neem oil in a 2-quart spray bottle. Medicinal or cosmetic neem products, including pricey essential oils, should never be used in the garden or for pesticidal purposes. Neem oil is a naturally occurring pesticide found in seeds from the neem tree. Find many great new & used options and get the best deals for 500ml Organic Neem Oil - 100% Pure - Natural Insecticide at the best online prices at eBay! Free delivery for many products! Be sure to spray the entire plant, including the tops and bottoms of the leaves as well as the stems. Natria Neem Oil is an easy to use option for Listed pests and diseases. Massage the shampoo into your pet’s coat and let it sit for five to ten minutes. Visit your local wilko at 11/15 Bridge Street in Walton On Thames for a huge range of hardware, homeware and garden products in. 00. It moisturizes your. Abstract and Figures. Use Neem Oil as a Systemic Treatment for Chewing & Sucking InsectsHarris Neem Oil is 100% Cold Pressed & Unrefined with absolutely no chemicals or additives included to ensure that the neem oil retains its original composition. Neem Oil as an Insecticide. Neem oil is used as an organic pesticide that kills a number of leaf-eating insects. All three Ingredients at this point will separate. (1) Email when in stock. Neem oil, however, is an extract obtained from the neem tree that is used as a natural pesticide and also has medicinal properties. Azadirachtin has a chemical composition that closely resembles. In late-winter, spread a thick layer of mulch around the base of the affected plant to prevent rain splashing soil-borne spores on to new spring growth. – Apply at the Right Time. Mix the neem oil solution well in a spray bottle and apply it to the top and the underside of all plant leaves to kill aphids efficiently. Next, spray the neem oil, water, and Castille soap mixture on the plants. Method. Neem oil, Tw20 and distilled water, or Hepes buffer (10 −2 M, pH 7. The Ready Seal Exterior Stain and Sealer for Wood is a great 2-in-1 stain and sealer that is easy to use and gives full protection against rain, mildew, and UV rays. Neem cake (the residue left after oil has been removed from the kernel) has proved so successful that Philippine farmers are already using it on a trial basis against the brown planthopper (and other rice pests). Neem oil is not recommended for particularly thin hair, as it can weigh hair down. Plan ahead so that you don’t use neem oil before a harvest. f28d23ddd9557fdd. It fades scars. Controls aphids, whiteflies and spider mites. Four different concentrations of neem oil were. The top adverse reaction is listed as increased muscle activity in 56 cases. Transfer the mixture into a spray bottle, and thoroughly spray your plants. A single seed may contain up to 50 percent oil by weight. Apply the mixture to a small test area on plants before treating the. However, it can burn plant leaves in the hot sun. Clarified hydrophobic neem oil, is an oil, and as such it does coat insects and can suffocate certain types of insects, including adults. Neem Oil for Dry Hair. Before applying it to the entire plant, you should first test it on a leaf or. A. Wilko: B&M strikes deal to buy 51 stores for up to £13m; Retailers look on sunny side as. Neem oil. Keep in mind that the purpose of the liquid soap is to serve as an emulsifier for the mixture. Use neem oil for houseplant gnats and other bugs, too. Happily for gardeners, neem oil is typically harmless to beneficial bugs that don’t. These. 3 Pack Pure Essential Aroma Oils - Pro Therapeutic Grade - Lavender, Peppermint - Lamp Oil for Relaxation and Refreshment. Add a few drops of essential neem oil to lemon juice for a true brightening experience. But no matter how you look at it, this oil is amazing. Neem Oil Is a Natural Fungicide. Plastic spray bottle. A little over a year ago, I had a strong well-rooted Hardy Chicago cutting with a bright and healthy future ahead of it. Maintain a healthy circulatory, digestive and respiratory system. minimize grays. Controls aphids, whiteflies and spider mites. 31 x 2. Pure Neem Oil may be applied as a foliar spray. 1. 20-30 drops peppermint oil. The main chemical constituents of Neem Carrier Oil are: Oleic Acid, Palmitic Acid, Stearic Acid, Linoleic Acid, Vitamin C, and Carotenoids. 1 quart: add ½ tsp of castile soap to 1 quart of water, then add 1 ½ tsp of neem oil. 100ml Neem Oil - Ideal to make a quality neem Spray - Natural Organic Garden Use. Pests and diseases that can affect chicken flocks can be controlled by spraying them. Though neem is relatively new to western civilization, it has been used for many centuries by people in India for its wide range of benefits. Get directions. Colgate Cavity Protection Toothpaste with Fluoride is our overall best pick and a great bargain. When used on food, it effectively kills and reduces pests while leaving no residue in the soil. As Neem Oil is an oil, it's thicker than water and doesn't mix well with it. 6 Effects on Other Organisms.